Sleep disturbance and cholinergic degeneration in Alzheimer's disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1049236

Funding Status
Closed

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Funded Activity Summary

The largest class of drugs given to Alzheimer's disease patients aims to increase the function of cholinergic neurons that degenerate early in the disease. We will test whether disturbed sleep, which has been linked to Alzheimer's disease and cognitive decline are caused by neurodegeneration of these neurons, and whether early treatment can slow disease progression.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $860,912.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Central Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Alzheimer disease | animal model | cholinesterase inhibitor | neurodegeneration | neurotrophins | sleep disorders

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