Molecular insights into long noncoding RNA-protein complexes: important gene regulators in cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1048659

Funding Status
Closed

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Funded Activity Summary

Cancer cells turn good genes off and bad ones on: but how do they do this? Recent breakthroughs suggest that noncoding RNA, produced from so-called ‘junk’ DNA, is important. One such noncoding RNA forms paraspeckles, a novel component of the cell machinery. Here, we will pick apart the way paraspeckles are organised and function, to develop them as a prototype for designing anti-cancer treatments against noncoding RNAs.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $388,927.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Genome Structure and Regulation

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

RNA | RNA binding proteins | RNA processing | gene expression | gene regulation | molecular basis of disease | protein complexes

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