Investigation of lipid-protein interactions of mechanosensitive ion channels

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1047980

Funding Status
Closed

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Funded Activity Summary

Living organisms are imminently exposed to mechanical stimuli such as gravity, touch or sound. Sensing mechanical stimuli is therefore crucial for survival. One biological tool for sensing mechanical stress are the mechanosensitive ion channels that open in response to tension in cell membranes. We will study the interactions and coupling between membrane lipids and mechanosensitive ion channels. These interactions are essential for the function of these fascinating sensory biological molecules.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $409,785.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Receptors and Membrane Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

confocal microscopy | electrophysiology | fluorescence spectroscopy | ion channels | lipids | mechanotransduction | modelling | patch clamp

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