Inhibitors Of Class II HDACs In Inflammatory And Metabolic Disease

Funding Activity

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Funded Activity Summary

Inflammatory diseases such as arthritis and inflammatory bowel syndrome are major social and economic burdens on Australian communities. Obesity, diabetes and cardiovascular disease are also now widely viewed as inflammatory diseases. New specialised types of anti-inflammatory drugs are urgently needed to treat such diseases. This project proposes to create new classes of anti-inflammatory drugs by altering anti-cancer drugs called histone deacetylase inhibitors.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $615,774.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Toll-like receptors | drug design | histone deacetylase | inflammation | inflammatory bowel disease (IBD) | macrophages | medicinal chemistry | obesity | rheumatoid arthritis | transgenic mouse