Capturing New Drugs That Selectively Modulate PAR2 Signaling Pathways

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1047759

Funding Status
Closed

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Funded Activity Summary

Infection and tissue damage provoke acute inflammatory responses that sometimes continue unchecked, leading to different kinds of debilitating inflammatory diseases and cancers. We have discovered a new class of drugs that bind to a new target on human cells and block undesirable prolonged inflammatory responses. This project tests a new strategy to produce 'cleaner' drugs that act more selectively with fewer side effects against a new target in the treatment of arthritis and other inflammatory diseases, diet-induced obesity and cancers.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $469,088.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biologically Active Molecules

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

arthritis | cancer | cardiovascular disease prevention | fibrosis | inflammation | inflammatory bowel disease (IBD) | medicinal chemistry | obesity | protease inhibitors | protease-activated receptors

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