Integrative bioinformatic and experimental approaches to define novel roles for genes that typically regulate Axon Guidance in pancreatic cancer initiation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1047334

Funding Status
Closed

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Funded Activity Summary

Early detection and intervention would have a dramatic effect on improving the outcomes for pancreatic cancer. This however relies on understanding how the cancer is initiated. New analysis of more than 100 tumours identified aberrations in genes that typically regulate how the nervous system is positioned during development. We want to use novel bioinformatic approaches and a unique experimental method with cells in culture to rapidly and accurately find out which of these genes drives a normal pancreatic cell to become a tumour cell.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $587,955.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Solid Tumours

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

axon guidance | bioinformatics | carcinogenesis | mouse models | pancreas

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