The regulation and function of strawberry notch in neuroinflammation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1047265

Funding Status
Closed

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Funded Activity Summary

Inflammation is a response to injury and infection that may cause significant damage to the brain. This project will study the regulation and function of a novel gene called strawberry notch that we have identified is a major target of the protein IL-6 which is a central mediator of inflammation in the brain. The findings will advance our understanding of the function of Sbno2 in the context of the actions of IL-6 and will provide crucial new mechanistic insights into a cause of neurological disease.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $733,598.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cytokines | glia | interleukin-6 (IL-6) | neuroinflammation | signal transduction

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