Endosomal protein trafficking complexes - therapeutic targets for novel antivirals

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1047243

Funding Status
Closed

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Funded Activity Summary

The enzyme Vps4 is a key target for the development of new antiviral drugs targeting a family of enveloped viruses that includes HIV (17,000 cases), Hepatitis B and C (420,000 cases) and Herpes Simplex (type I, II - 1.3 million cases). This project will use high resolution microscopy to investigate the molecular structures that enable infection by these and other Vps4-dependent enveloped viruses.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $543,727.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

electron microscopy | molecular mechanisms | protein complexes | protein-protein interaction | structural biology

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