The Therapeutic Role of Complement Inhibition in ANCA Associated Glomerulonephritis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1046585

Funding Status
Closed

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Funded Activity Summary

ANCA associated vasculitis is an inflammatory disease involving the kidney filters which is a major cause of chronic kidney failure. Current drugs to treat it are toxic. Less toxic treatments are required. In this study we will explore the potential for new treatments targeting complement (a normal blood protein involved in inflammation) to attenuate this disease in mice. We hope to define the role of complement in this disease and the benefits of inhibiting it before we use it in humans.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $600,964.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nephrology and Urology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

complement | complement C5a | experimental glomerulonephritis | glomerulonephritis | kidney failure | renal failure | vasculitis

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