Structure-based design of inhibitors of PimA - a new target for tuberculosis therapy

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1045995

Funding Status
Closed

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Funded Activity Summary

Tuberculosis (TB) is a devastating disease that kills 2 million people worldwide each year and affects one-third of the entire human population. Bacterial resistance to existing antibiotics is an ever increasing problem, highlighting the need to develop new anti-TB drugs. The aim of this project is to develop specific inhibitors to target a protein that is essential for the survival of the tuberculosis bacterium.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $666,246.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

enzyme inhibitors | medicinal chemistry | structure-activity relationships | structure-based drug design | tuberculosis

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