Structural and mechanical determinants of airway hyperresponsiveness

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1045824

Funding Status
Closed

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Funded Activity Summary

In asthma and chronic obstructive pulmonary disease, the capacity for airway passages to narrow is increased which limits airflow in and out of the lung and contributes to disease severity. The aim of this project is to identify the underlying physiological abnormalities producing the increased narrowing capacity. The investigations will focus on the role of the airway smooth muscle and epithelial layers that are widely implicated in driving the increased narrowing response, but for which the evidence remains circumstantial.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Career Development Fellowships

Funding Amount: $415,219.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

airway hyper-responsiveness | airway smooth muscle | asthma | chronic obstructive pulmonary disease (COPD) | epithelium | imaging | mechanical ventilation | physiology | structure-function

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