Identification and therapeutic modulation of sphingolipids as novel lung macrophage-targeted treatments for COPD/emphysema

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1045514

Funding Status
Closed

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Funded Activity Summary

COPD/emphysema is predicted to be the third leading cause of death woldwide by 2010. We have shown defective lung macrophage function in COPD and have shown that we can modify the macrophage function with novel therapies. We are now investigating a specific “sphingosine” pathway to see if it can provide us with more specific information. We aim to provide a better, more specific, adjunct treatment for the disease.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $694,704.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

emphysema | mouse models | smoking-related diseases | sphingolipids | treatment strategies

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