Annexin-A1 Agonists Rescue Cardiac Contractile Function After Myocardial Infarction

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1045140

Funding Status
Closed

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Funded Activity Summary

Myocardial infarction (or heart attack, a result of reduced coronary blood flow) and subsequent heart failure are the major cause of death in Western societies; this is expanding to all corners of the globe. New treatments for heart attack are thus essential. We have discovered that the natural hormone annexin-A1 rescues heart muscle function over the short-term, and propose that drugs based on annexin-A1 will prevent cardiac dysfunction of heart muscle up to several weeks after heart attack.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $621,419.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cardioprotection | ischaemic heart disease | myocardial reperfusion injury | therapeutic agents | ventricular dysfunction

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