Elucidating the pathogenic role of rotavirus infection in type 1 diabetes development

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1044868

Funding Status
Closed

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Funded Activity Summary

Rotavirus infection is the main cause of severe diarrhoea in children, and has been implicated in accelerated progression of genetically at-risk children towards type 1 diabetes in two independent studies. My group has further discovered that rotavirus also accelerates diabetes onset in mice in a novel immunological process. In this project, we will determine the mechanism behind this disease exacerbation in the mice, to facilitate understanding of the process in children.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $535,579.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Virology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

NOD mouse | autoimmunity | diabetes prevention | lymphocytes | pancreatic islets | rotavirus | rotavirus infection | type 1 diabetes mellitus (insulin-dependent diabetes mellitus) | viral immunology | virus pathogenesis

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