Roles of muscarinic M3 receptors in antipsychotic-induced metabolic side-effects: prevention and treatment of antipsychotic-induced insulin dysregulation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1044624

Funding Status
Closed

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Funded Activity Summary

Antipsychotic drugs are used to treat various mental disorders, such as schizophrenia, bipolar disorder, dementia and major depression. However, these drugs cause serious metabolic side-effects leading to premature death and huge costs to the Australian health care system. This project aims to reveal the role of muscarinic M3 receptors in antipsychotic-induced insulin dysregulation that precedes diabetes. Understanding these mechanisms will provide new strategies for the prevention and treatment of these critical adverse effects.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $603,825.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Psychiatry (incl. Psychotherapy)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antipsychotic drugs | metabolic syndrome | muscarinic receptors | schizophrenia | side-effects

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