The regulation of IgE antibody production by antigen-specific B cells

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1044477

Funding Status
Closed

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Funded Activity Summary

Asthma and other allergies are caused by the inappropriate production of IgE antibodies by the immune system. IgE is not produced in response to most infections but the controls that normally prevent IgE production are unknown. We have identified two separate molecules that prevent IgE production during immune responses. In this proposal we aim to investigate how these controls work. This information may help to devise strategies for controlling IgE production and therefore allergic disease.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $454,105.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Allergy

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

allergy | antibody production | germinal centre | immunoglobulin E (IgE) | lymphocyte differentiation

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