Mucosal vaccine for Hendra virus

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1044332

Funding Status
Closed

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Funded Activity Summary

Hendra virus (HeV) cause a disease transmitted from bats to horses which in turn infect humans and other horses. There are no drugs or vaccines for HeV. Since humans are infected by inhalation, a vaccine that can generate antibody in the lung and protect from infection will be ideal. We have found that a natural sugar called mannan used with virus proteins and administered via the nostrils to generate such responses. In this project we will prepare this vaccine and use it in a mouse model of HeV infection to see if it can protect the mice.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Targeted Calls

Funding Amount: $191,582.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Humoural Immunology and Immunochemistry

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adjuvant | infectious diseases | mucosal vaccination | vaccine development | viral vaccines

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