The role of dicarbonyl-derived AGEs and RAGE in diabetes associated atherosclerosis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1044097

Funding Status
Closed

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Funded Activity Summary

Based on our pilot data we postulate that glucose derived molecules such as methylglyoxal (MGO) have effects on inflammation and oxidative stress leading to accelerated atherosclerosis in diabetes. Our studies aim to identify novel treatments which block these effects thus leading to superior protection and prevention of atherosclerosis in diabetes.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $470,617.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Endocrinology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

atherosclerosis | diabetes mellitus | diabetic vascular complications | glycation | macrophages

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