Regulation of normal and malignant haematopoiesis by the bone marrow environment

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1044091

Funding Status
Closed

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Funded Activity Summary

This project will identify factors within the bone marrow that regulate blood and immune cell formation. These include oxygenation and novel proteins identified in the applicant’s laboratory. How these factors from the bone marrow influence the behaviour of normal blood forming cells (called haematopoietic stem cells), and the progression of leukaemia and the response of leukaemia to chemotherapy treatments will be investigated. New drugs that interfere with these new factors will be tested for their potential to treat leukaemia.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2017

Funding Scheme: Research Fellowships

Funding Amount: $621,458.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

bone marrow stroma | bone marrow transplantation | haematopoiesis | haematopoietic stem cells | hypoxia | leukaemia | microenvironment

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