Taking the First Steps from Promise to Product: Exploration of the Newly Discovered Interleukin 37 Receptor Complex and Its Signaling Pathways

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1043845

Funding Status
Closed

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Funded Activity Summary

Cytokines are messenger proteins used by most cells of the body. They function as master regulators of many biological processes and as such play an important role in a wide spectrum of diseases. Anti-inflammatory cytokines attenuate the potentially destructive force of other cytokines and the immune system as a whole, and are therefore coveted as drug targets. We discovered the formidable anti-inflammatory properties of IL-37 and will now explore how these activites can be utilised in clinical medicine.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $694,623.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

anti-inflammatory agents | crystallization | drug development | immunology | inflammation | protein engineering | receptor binding | recombinant proteins | signalling pathways

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