Does Excess Consumption of Dietary Advanced Glycation End Products activate the Complement Pathway Contributing to Diabetic Nephropathy?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1043753

Funding Status
Closed

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Funded Activity Summary

Modern lifestyle is characterised by the consumption of foods that have been highly processed to improve their shelf life and flavour. However, this food processing has been shown to generate potentially harmful compounds, Advanced Glycation End Products (AGEs) that may promote inflammation and worsen diabetic kidney disease. This study investigates the effects of overeating a diet high in AGEs on the function of the kidney, and aims to find out how these AGEs lead to kidney damage.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $470,617.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

complement | diabetic nephropathy | glycation | kidney disease | nutrition | therapy

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