Reversing autoimmune diabetes by controlling pathogenic effector T-cells

Funding Activity

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Funded Activity Summary

Type 1 diabetes (T1D) results from misdirected immune responses that destroy insulin-producing pancreatic cells. The ultimate goal of therapeutic strategies is to remove or inactivate the cells that attack insulin-producing cells, while leaving other cells, for example, those required for protection from infectious diseases and tumours, unaffected. Here we propose to test a new way of turning off the inappropriate immune reaction with the goal of preventing type 1 diabetes.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $408,662.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antigen presenting cells | autoimmune disease | gene therapy | tolerance | type 1 diabetes mellitus (insulin-dependent diabetes mellitus)