Mechanism of action and targeting of RAGE in inflammation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1043095

Funding Status
Closed

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Funded Activity Summary

Humans have evolved defense and repair mechanisms to counteract threats such as tissue injury and infection. The immune system first must detect the potential life-threatening event and it does so by recognizing danger signals. RAGE is a key cell-surface receptor that recognises these danger signals. Despite its important role in health and disease our understanding of how RAGE works is very limited. We will discover how RAGE works and how to manipulate its function for new infection therapies.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $386,423.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Receptors and Membrane Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

biochemistry | infection | inflammation | innate immunity | protein chemistry

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