Understanding how perforin forms pores: the role of calcium and lipids.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1042858

Funding Status
Closed

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Funded Activity Summary

This grant aims to study perforin, a key part of the mammalian immune system. The work will facilitate the development of perforin inhibitors. It is anticipated that these data will be of utility in developing first in class drugs to improve the success of bone marrow transplantation.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $797,813.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

calcium | crystallography | lipids | nuclear magnetic resonance (NMR) spectroscopy | perforin

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