Role of autotransporter proteins in uropathogenic E. coli infections

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1042651

Funding Status
Closed

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Funded Activity Summary

Urinary tract infections (UTI) are among the most common infectious diseases of humans. Uropathogenic E. coli (UPEC), the primary cause of UTI, utilize a range of adherence mechanisms to colonize the urinary tract. In this project we will characterise the function and mode of secretion for one important class of UPEC adherence factors – autotransporter proteins. This work may inform new approaches to prevent UTI, an urgent need given the rapid increase in resistance to antibiotics among UPEC.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $611,149.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Bacteriology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Escherichia coli | bacterial biofilm | bacterial pathogenesis | bacterial virulence | bacterial virulence factors | urinary tract infection (UTI)

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