Novel therapeutic phenotyping for sleep apnoea - A paradoxical role for sedatives

Funding Activity

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Funded Activity Summary

Sleeping pill (sedative) use has risen dramatically. Sedatives may worsen a common breathing condition called obstructive sleep apnoea (OSA). Accordingly, their use has been discouraged in OSA. However, recent studies indicate that certain sedatives may actually reduce OSA severity in some patients. By studying the effects of common sedatives on OSA and breathing, this proposal aims to explain these apparent paradoxical responses and ultimately provide a new treatment approach for OSA.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $639,168.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

arousal | sleep apnoea | sleep breathing disorders | upper airway muscles | upper airway physiology