Microenvironmental Impact in the Treatment of Acute Lymphoblastic Leukemia

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1042305

Funding Status
Closed

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Funded Activity Summary

Acute lymphoblastic leukemia remains one of the leading causes of death in children and outcomes for adults with this disease remain poor. This project examines how manipulation of the environment where leukemia arises can be used to therpaeutic advancage. Acute lymphoblastic leukemia cells are highly dependent on the support provided by bone marrow cells but the mechanisms are not well understood. Disrupting signals from the bone marrow cells has potential as a therapeutic strategy.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2017

Funding Scheme: Research Fellowships

Funding Amount: $621,458.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Haematology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

chemotherapy | leukaemia | microenvironment | mouse models | stem cell biology

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