Understanding how membrane trafficking controls the levels of Alzheimer's disease causing A? peptides

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1042082

Funding Status
Closed

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Funded Activity Summary

Alzheimer’s disease is a progressive neurological disorder and is the most common cause of dementia. No effective treatments are currently available. The toxic amyloid peptide is central to disease pathology and is derived from breakdown of the Alzheimer’s amyloid precursor protein (APP). In this project we will examine the interactions between APP and the molecular machinery that controls its location in the cell and subsequent degradation.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $478,905.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurosciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Alzheimer disease | X-ray crystallography | amyloid precursor protein | endosomes | membrane trafficking | molecular neuroscience | neurodegenerative disorders | protein trafficking | protein-protein interaction

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