Effects of Hypothalamus-specific NPY Y1 and Y5 Receptor Deletion in High Fat Diet-induced Obesity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1039736

Funding Status
Closed

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Funded Activity Summary

Obesity is a rising global epidemic, contributing to severe morbidity and mortality and extreme financial burden on society. It is known that the brain controls energy metabolism via molecules such as neuropeptide Y, which has two key receptors involved in weight gain, Y1 and Y5. This study looks at deleting Y1 and Y5 in the brain of overfed subjects to demonstrate their involvement in metabolic adaptations that prevent weight gain in overfeeding, thus developing effective weight loss therapies to treat obesity.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $60,420.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurosciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

body weight regulation | central nervous system (CNS) | hypothalamus | neuropeptide Y (NPY) | obesity

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