The role of stellate cells in fibrosis and liver disease progression in HIV-Hepatitis B co-infection

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1039055

Funding Status
Closed

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Funded Activity Summary

Liver related mortality is the commonest cause of non-AIDS death in HIV infected individuals on treatment. With HIV, HBV liver damage is accelerated and liver-related mortality increased. Understanding how and why is critical to management. I will examine the role of hepatic stellate cells using in vitro models and directly ex vivo from infected patient biopsy tissue. I will investigate the activated of these cells by HIV and HBV infection, thus promoting scar formation with liver injury.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2017

Funding Scheme: Postgraduate Scholarships

Funding Amount: $157,292.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

fibrosis | hepatitis | hepatitis B infection | human immunodeficiency virus (HIV) | stellate cells

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