The role of signal transducer and activator of transcription- (STAT) related proteins in dendritic cells during chronic active infections

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1039014

Funding Status
Closed

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Funded Activity Summary

Chronic infections produced by pathogens such as HIV, overwhelm our immune system leading to an exhausted state where cells responsible for the clearance of invading microorganisms are unable to respond effectively. We have recently identified a highly promising therapeutic target that enhances immune effector function. We seek to understand the underlying mechanism, and to explore its therapeutic potential for use as a common platform to treat diverse infections.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Postgraduate Scholarships

Funding Amount: $95,313.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cell immunity | adaptive immunity | chronic infection | dendritic cell | therapeutics | translational research

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