The characterisation of the functional regions of sarcomeric alpha-actinins and to determine how the absence of alpha-actinin-3 influences human skeletal muscle function and metabolism.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1038991

Funding Status
Closed

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Funded Activity Summary

We are studying a muscle protein called a-actinin-3. This protein is absent in approximately one billion people worldwide. A-actinin-3 is associated with athletic performance. Our goal is to explore how the absence of a-actinin-3 influences human skeletal muscle function and metabolism. We will be studying a-actinin-3 deficiency using a mouse model.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Postgraduate Scholarships

Funding Amount: $95,313.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

functional genomics | genetics | molecular biology | molecular mechanisms | mouse models | muscle function | protein interactions | recombinant proteins

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