The biophysical basis of HCN channels in human peripheral nerve

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1038791

Funding Status
Closed

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Funded Activity Summary

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels play an important role as pacemakers in the cardiac and nervous systems. HCN channel dysfunction is implicated in a number of disorders including neuropathic pain and epilepsy. My aim is to determine the kinetics and voltage dependence of HCN channels in human peripheral nerve in vivo. Understanding these channels is a prerequisite to the development of safe targeted therapies against neuropathic pain.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2013

Funding Scheme: Postgraduate Scholarships

Funding Amount: $50,315.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Peripheral Nervous System

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

accommodation | action potential | axonal excitability | human | ion channels | mathematical modelling | peripheral nerve

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