To describe the regional differences in the innate immune system of the skin using intra-vital multiphoton microscopy and understand its functional consequences in a cutaneous parasite infection model.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1038704

Funding Status
Closed

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Funded Activity Summary

This study is the first of its kind to map the innate immune system, the body's first line of defence, in the skin - coined the "immune atlas". Researchers have shown regional differences in innate immune cells which could explain how infections develop at different sites of the body. Although they have shown this in a cutaneous leishmaniasis model, a parasite endemic in most parts of the world, it may have implications also for inflammatory skin conditions such as eczema or psoriasis.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: NHMRC Postgraduate Scholarships

Funding Amount: $97,182.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cellular interactions | dermatology | imaging | infection | innate immunity | leishmaniasis | skin immunology | skin infections

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