Suppression of immunity by the malaria parasite antigen Plasmodium falciparum Erythrocyte Membrane Protein-1 (PfEMP-1)

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1038030

Funding Status
Closed

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Funded Activity Summary

The malaria parasite P. falciparum infects red blood cells and makes the cells put on their surface a protein called PfEMP-1. The parasite can effectively “hide” by constantly changing this protein and making it unrecognizable by the immune system. PfEMP-1 can also suppress the immune system so that it can’t respond adequately to infection. Therefore, understanding PfEMP-1 function is important. I will investigate how PfEMP-1 can do this by looking at its cross talk with the immune system.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Postgraduate Scholarships

Funding Amount: $96,698.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Toll-like receptors | cell signalling | host/pathogen interaction | immune evasion | immunosuppression | malaria

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