Antibodies to the invasion ligand EBA175 and protection from Plasmodium falciparum malaria

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1037722

Funding Status
Closed

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Funded Activity Summary

Malaria causes disease and death by invading into human red blood cells and it achieves this by using specific parasite proteins. One of these, erythrocyte binding antigen 175 (EBA175), is especially important and parasites have evolved different versions of the protein. This project seeks to understand the importance of these different EBA175 variants in evading antibody responses. This has important implications in understanding natural immunity but also for future vaccine development.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2016

Funding Scheme: Early Career Fellowships

Funding Amount: $407,792.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Parasitology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antibody | immunity | malaria | tropical disease | vaccine candidate molecules

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