Mitochondrial dysfunction in cardiac hypertrophy and failure

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1037702

Funding Status
Closed

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Funded Activity Summary

Heart failure is a disease of wide prevalence in the Western World. In addition to the human toll of heart failure, the economic impact is highly substantial. It remains unclear what causes heart failure, but the effects of calcium and free radicals produced in the mitochondria on muscle function are generally accepted as major contributors. The aim of this project is to understand how calcium and free radicals interact with each other and the mechanisms by which they reduce heart function.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2013

Funding Scheme: Early Career Fellowships

Funding Amount: $164,821.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Physiology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

calcium regulation | cardiac hypertrophy | heart failure | mitochondria | reactive oxygen species (ROS)

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