The role of self reactive T cells in the normal TCR repertoire

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1037298

Funding Status
Closed

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Funded Activity Summary

The immune system is highly regulated and sophisticated in order to distinguish foreign invaders from our own body. Once control is lost in this system, mistakes can happen, and autoimmunity, attack of ones self may result. Surprisingly potentially dangerous ‘fighter’ T cells can be readily found in healthy individuals whom are free from autoimmunity. The aim of this project is to understand how we can survive with these potentially harmful T cells around and what may activate them.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2016

Funding Scheme: Early Career Fellowships

Funding Amount: $363,601.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Autoimmunity

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cell development | autoimmune disease | autoimmunity initiation | cell activation | immune development | immune regulation | immune surveillance

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