Nuclear Sirtuins at the Interface between Epigenetic Regulation and Human Cytomegalovirus Pathogenesis: A Proteomics Perspective

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1037043

Funding Status
Closed

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Funded Activity Summary

Human cytomegalovirus (HCMV) is a human pathogen that infects over 60% of the adult population, and is a major cause of birth defects causing permanent hearing and vision loss, and mental retardation. To investigate the critical involvement of host epigenetic factors, I will study the roles of sirtuins during HCMV infection. Through proteomic, genomic, microscopy, and bioinformatic techniques, I aim to further our understanding of viral pathogenesis, towards developing novel therapies.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2016

Funding Scheme: Early Career Fellowships

Funding Amount: $399,488.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Systems Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

acetylation | cytomegalovirus (CMV) infection | epigenetics | protein complexes | protein interactions | protein localisation | proteomics | virology

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