Proteins involved in HIV infection and host defense

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/GNT1036521

Funding Status
Closed

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Funded Activity Summary

I am a biochemist focused on answering the question: why is it that humans are susceptible to HIV infection, while certain monkeys are resistant? It is known that these monkeys have evolved proteins which can target and destroy the virus, but the equivalent human proteins don’t work against HIV. I intend to compare the monkey and human proteins to understand how the monkeys destroy the virus and why the human protein is defective. These studies will inform the next generation of HIV treatment.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2018

Funding Scheme: Early Career Fellowships

Funding Amount: $323,244.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

biophysics | crystallography | host/pathogen interaction | human immunodeficiency virus (HIV) | protein function | protein structure | protein-protein interaction | structural biology | structural immunology | viral infection

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