Cellular response to modulation of iron levels: studies examining ASK1, thioredoxin and ribonucleotide reductase

Funding Activity

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Funded Activity Summary

Iron is crucial for many essential biological processes. Recently, I demonstrated that iron-depletion can affects signalling pathways that play important roles in cellular growth and death. This study is designed to investigate the cellular and molecular effects of iron depletion which currently remains unclear. My proposed research is crucial for understanding: (1) the effects of iron-deficiency and (2) for understanding the effects of iron chelators that are used for treating various diseases.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Early Career Fellowships

Funding Amount: $33,055.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer chemotherapeutic agents | cell biology | cell signalling | cellular mechanisms | chemotherapy treatment effects | drug development | iron chelators | pharmacological intervention | pharmacology