Development of specific modulators of voltage-gated sodium channels

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1035102

Funding Status
Closed

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Funded Activity Summary

This project will identify novel modulators of voltage-gated sodium (NaV) channels, a type of sodium-conducting integral membrane proteins, which play a central role in neuronal, muscular, and cardiac function. These modulators will be characterized in order to understand how they modify channel function and to aid their development as analgesics for the treatment of chronic pain.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Early Career Fellowships

Funding Amount: $384,479.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

channelopathy | drug discovery | high performance liquid chromatography (HPLC) | pain | patch clamp | peptide synthesis | protein purification | protein structure | sodium channel | venom

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