Rational development of novel analgesics for the treatment of chronic pain

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1034958

Funding Status
Closed

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Funded Activity Summary

Chronic pain is a major global health problem that currently affects over three million Australians. There are few drugs available for treatment of chronic pain and most have significant side-effects. Individuals lacking a particular type of ion channel known as Nav1.7 are completely insensitive to pain, but are otherwise normal. Block of this channel therefore appears to be an ideal avenue for pain relief. This project aims to produce selective Nav1.7 blockers that can be used as analgesics for treating chronic pain.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $595,945.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biologically Active Molecules

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

analgesia | chronic pain | drug design | ion channels | nuclear magnetic resonance (NMR) spectroscopy | pain minimisation | peptides | protein characterisation | protein structure | structural biology

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