Structural and biochemical investigation of the Bloom�s complex, defective in Bloom�s Syndrome

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1033592

Funding Status
Closed

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Funded Activity Summary

Bloom�s Syndrome is a rare inherited disorder that results in greater than 90% risk of developing cancer by the age of 25. The gene that causes Bloom�s Syndrome, called BLM, protects cells from cancer-causing mutations hence affected individuals develop the same types of cancers as the general population, only much faster. We will investigate the properties of the BLM gene product and understand how it protects us from cancer, and may influence some forms of cancer treatment.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $184,661.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA damage | DNA repair | cancer cell biology | enzyme-protein interactions | genetic disorders | protein biochemistry | protein complexes

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