Boosting mitochondria- a new approach for protecting the aging optic nerve in glaucoma

Funding Activity

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Funded Activity Summary

Increasing age is a major risk factor for neurodegeneration. We have recently shown that subjecting mice to intermittent periods of fasting improves mitochondrial function in the retina and reverses age-related decline in optic nerve vulnerability to injury. This project now aims to investigate key molecular pathway for restoring mitochondria and from this attempts to find more palatable therapeutic strategies for protecting the optic nerve from injury.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $391,784.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Ophthalmology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

ageing | glaucoma | mitochondria | neurodegeneration | neuroprotection | optic nerve