Identification of novel ERBB2 co-operating tumor suppressors using in vivo RNAi screens.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1032511

Funding Status
Closed

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Funded Activity Summary

Invasive breast cancer is often lethal, however, noninvasive disease has a >98% survival rate. Thus, understanding how breast cancer develops invasive ability is an important research goal. Using a new method in mice predisposed to breast cancer, we will find genes that prevent tumor invasion and determine if they are important in human cancer. By understanding how these genes restrict tumor invasion, we hope to develop therapies to improve breast cancer treatment.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

ErbB2-mediated cell signalling | RNA interference | breast cancer | mouse models | screening | tumour suppressor gene

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