How intra-abdominal transplantation of subcutaneous adipose tissue prevents high-fat diet-induced insulin resistance and obesity

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1031769

Funding Status
Closed

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Funded Activity Summary

In obese humans, storing excess fat within the abdomen is associated with the development of adult-onset diabetes and cardiovascular disease. However, the mechanisms linking intra-abdominal fat accumulation with these diseases are not well understood. We have studied intra-abdominal fat accumulation in mice using a transplant model, and we have found that transplanting subcutaneous fat intra-abdominally prevents diet-induced obesity and glucose intolerance. We aim to investigate the underlying mechanisms.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $358,465.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Endocrinology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adipose tissue | energy balance | glucose intolerance | insulin resistance | obesity

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