Failure of donor antigen presentation promotes IL-17 dependant chronic GVHD

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1031728

Funding Status
Closed

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Funded Activity Summary

Bone marrow transplantation (BMT) is the most effective treatment for a number of haematological conditions, especially leukemia. Graft versus host disease (GVHD) is a complication of BMT and results in the death of up to 50% of transplant recipients. GVHD occurs when the newly transplanted immune system recognizes the recipient as foreign and mounts and immune reponse against the patients tissues. These studies will focus on identifying and understanding the function of the immune cells which drive GVHD.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $585,860.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Transplantation Immunology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

antigen presentation | antigen presenting cells | bone marrow transplantation | graft versus host disease (GVHD) | transplantation biology

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