Investigations into supraphysiologic T cell receptors and T cell agonists.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1031652

Funding Status
Closed

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Funded Activity Summary

T cells are critical in controlling infection and important for the natural eradication of cancer. Through shape recognition, T cells identify dangerous antigens via the surface-bound T cell receptor (TCR). Using new technologies this project aims to "tune up" the strength of this molecular interaction and create a new generation of high affinity TCR and antigens for use as therapeutic and prophylactic drugs in the battle against infectious disease and cancer.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Career Development Fellowships

Funding Amount: $408,388.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Epstein-Barr virus (EBV) | T cell epitope | T cell receptor | T cells | drug design | vaccine candidate molecules

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