Immune modifying particles - a novel therapeutic strategy to treat West Nile Virus encephalitis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1030897

Funding Status
Closed

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Funded Activity Summary

The outcome of viral infection of the brain is determined by the attraction of white blood cells, especially monocytes into the brain. Monocytes have a paradoxical role during brain inflammation. On one hand they are essential defenders against viral infection. On the other they may cause lethal brain damage. This project aims to define the mechanism(s) through which a novel therapeutic strategy, known as immune modifying particles, can modulate monocytes migration and function during brain infection.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $550,926.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Biotechnology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

anti-inflammatory | dendritic cell | encephalitis | immunopathology | microspheres | monocyte/macrophage differentiation | nanotechnology

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